Ketamine & Related Compounds International Journal Club
A series of free, short, 30-minute webinars held every two weeks, held on the 2nd and 4th Tuesdays at 12:30pm EST (usually 9:30am Pacific, 5:30pm GMT, 11:00pm Indian Standard).
Upcoming Journal Club Presentations
56. Ketamine’s mechanism of action with an emphasis on neuroimmune regulation: can the complement system complement ketamine’s antidepressant effects?
Ketamine’s mechanism of action with an emphasis on neuroimmune regulation: can the complement system complement ketamine’s antidepressant effects?Tuesday 11th June 2024 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Brandi Quintanilla, Carlos A....
Past Journal Club Presentations
55. Predicting non-response to ketamine for depression: An exploratory symptom-level analysis of real-world data among military veterans.
Predicting non-response to ketamine for depression: An exploratory symptom-level analysis of real-world data among military veteransTuesday 28th May 2024 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Eric A. Miller, Houtan Totonchi Afshar,...
54. Clinical predictive factors and trajectories of suicidal remission over 6 weeks following intravenous ketamine for suicidal ideation
Clinical predictive factors and trajectories of suicidal remission over 6 weeks following intravenous ketamine for suicidal ideationTuesday 13th February 2024 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Fabrice Jollant, Christophe Demattei,...
53. Exploring Predictors of Ketamine Response in Adolescent Treatment-Resistant Depression
Exploring Predictors of Ketamine Response in Adolescent Treatment-Resistant DepressionTuesday 23rd January 2024 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Alice Lineham, MRes, Victor J. Avila-Quintero, MD, Michael H. Bloch, MD, MS, Jennifer...
52. Preliminary evidence that ketamine alters anterior cingulate resting-state functional connectivity in depressed individuals
Preliminary evidence that ketamine alters anterior cingulate resting-state functional connectivity in depressed individualsTuesday 12th December 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Journal: Transl Psychiatry. 2023 Dec...
51. Three daily intraperitoneal injections of sub-anesthetic ketamine ameliorate activity-based anorexia vulnerability of adult female mice
Three daily intraperitoneal injections of sub-anesthetic ketamine ameliorate activity-based anorexia vulnerability of adult female miceTuesday 28th November 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Sebastian Goodwin-Groen, Yiru Dong,...
50. Ketamine uropathy: Clinical experience in a high prevalence center
Ketamine uropathy: Clinical experience in a high prevalence centerTuesday 14th November 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)George Sturgess, Ian Beckley, Robin Shepherd, Alison Downey.Neurourol Urodyn. 2023 Sep;42(7):1555-1562....
49. Randomized Trial of Ketamine Masked by Surgical Anesthesia in Depressed Patients
Randomized Trial of Ketamine Masked by Surgical Anesthesia in Depressed PatientsTuesday 24th October 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Theresa R Lii, Ashleigh E Smith, Josephine R Flohr, Robin L Okada, Cynthia A Nyongesa, Lisa...
48. Comparative Effectiveness of Intravenous Ketamine and Intranasal Esketamine in Clinical Practice Among Patients With Treatment-Refractory Depression: An Observational Study
Comparative Effectiveness of Intravenous Ketamine and Intranasal Esketamine in Clinical Practice Among Patients With Treatment-Refractory Depression: An Observational StudyTuesday 12th September 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA...
47. Assessment of Initial Depressive State and Pain Relief With Ketamine in Patients With Chronic Refractory Pain
Assessment of Initial Depressive State and Pain Relief With Ketamine in Patients With Chronic Refractory PainTuesday 8th August 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Marion Voute, Céline Lambert, Bruno Pereira, Gisèle...
46. Long term structural and functional neural changes following a single infusion of Ketamine in PTSD
Long term structural and functional neural changes following a single infusion of Ketamine in PTSDTuesday 26th July 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Or Duek, Nachshon Korem, Yutong Li, Ben Kelmendi, Shelley Amen, Charles...
45. Intravenous ketamine for treatment-resistant depression patients who have failed to respond to transcranial magnetic stimulation: A case series
Intravenous ketamine for treatment-resistant depression patients who have failed to respond to transcranial magnetic stimulation: A case seriesTuesday 27th June 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Olivier Payette, Paul...
44. Changes in white matter microstructure following serial ketamine infusions in treatment resistant depression
Changes in white matter microstructure following serial ketamine infusions in treatment resistant depressionTuesday 13th June 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Brandon Taraku, Roger P. Woods, Michael Boucher, Randall Espinoza,...
43. Association of the delayed changes in glutamate levels and functional connectivity with the immediate network effects of S-ketamine
Association of the delayed changes in glutamate levels and functional connectivity with the immediate network effects of S-ketamineTuesday 23rd May 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Lena Vera Danyeli, Zümrüt Duygu Sen, Lejla...
42. Characterizing brain dynamics during ketamine-induced dissociation and subsequent interactions with propofol using human intracranial neurophysiology
Characterizing brain dynamics during ketamine-induced dissociation and subsequent interactions with propofol using human intracranial neurophysiologyTuesday 25th April 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Fangyun Tian, Laura D...
41. Sympathetic Blocks as a Predictor for Response to Ketamine Infusion in Patients with Complex Regional Pain Syndrome: A Multicenter Study
Sympathetic Blocks as a Predictor for Response to Ketamine Infusion in Patients with Complex Regional Pain Syndrome: A Multicenter StudyTuesday 28th March 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Steven P Cohen, Chachrit...
40. A pilot randomized controlled trial of ketamine in Borderline Personality Disorder
A pilot randomized controlled trial of ketamine in Borderline Personality DisorderTuesday 14th March 2023 | 04:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Sarah K Fineberg, Esther Y Choi, Rosa Shapiro-Thompson, Khushwant Dhaliwal, Eli Neustadter,...
39. Real-world effectiveness of repeated ketamine infusions for treatment-resistant bipolar depression
Real-world effectiveness of repeated ketamine infusions for treatment-resistant bipolar depressionTuesday 28th February 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Farhan Fancy, Nelson B. Rodrigues, Joshua D. Di Vincenzo, Edmond H. Chau,...
38. Patients’ recovery and non-recovery narratives after intravenous ketamine for treatment-resistant depression
Patients' recovery and non-recovery narratives after intravenous ketamine for treatment-resistant depressionTuesday 14th February 2023 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Adrienne Lapidos, Daniela Lopez-Vives, Cortney E Sera,...
37. Intravenous ketamine for depression: A clinical discussion reconsidering best practices in acute hypertension management
Intravenous ketamine for depression: A clinical discussion reconsidering best practices in acute hypertension managementTuesday 22nd November 2022 | 05:30 PM (UK time) | 10:30 AM (MST Edmonton time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Ryan Yip, Jennifer...
36. Evaluation of Early Ketamine Effects on Belief-Updating Biases in Patients With Treatment-Resistant Depression
Evaluation of Early Ketamine Effects on Belief-Updating Biases in Patients With Treatment-Resistant DepressionTuesday 25th October 2022 | 05:30 PM (BST UK time) | 06:30 PM (CEST France time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Hugo Bottemanne, MD; Orphee...
35. A Novel, Brief, Fully Automated Intervention to Extend the Antidepressant Effect of a Single Ketamine Infusion: A Randomized Clinical Trial
A Novel, Brief, Fully Automated Intervention to Extend the Antidepressant Effect of a Single Ketamine Infusion: A Randomized Clinical TrialTuesday 11th October 2022 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Rebecca B. Price, Ph.D., Crystal...
34. The Pharmacokinetics of Ketamine in the Breast Milk of Lactating Women: Quantification of Ketamine and Metabolites
The Pharmacokinetics of Ketamine in the Breast Milk of Lactating Women: Quantification of Ketamine and MetabolitesTuesday 27th September 2022 | 12.30pm EST | 5.30pm UKPhilp Wolfson, Rob Cole, Kara Lynch, Cassandra Yun, Jason Wallach, Julane Andries, Melissa Whippo.J...
33. Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2
Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2Tuesday 13th September 2022 | 12.30pm EST | 5.30pm UKJuan Pablo Lopez, Malte D Lücken, Elena Brivio, Stoyo Karamihalev, Aron Kos, Carlo De Donno, Asaf Benjamin, Huanqing...
32. At-home, sublingual ketamine telehealth is a safe and effective treatment for moderate to severe anxiety and depression: Findings from a large, prospective, open-label effectiveness trial
At-home, sublingual ketamine telehealth is a safe and effective treatment for moderate to severe anxiety and depression: Findings from a large, prospective, open-label effectiveness trialTuesday 26th July 2022 | 12.30pm EST | 5.30pm UKThomas D Hull, Matteo Malgaroli,...
31. Mapping consent practices for outpatient psychiatric use of ketamine
Mapping consent practices for outpatient psychiatric use of ketamineTuesday 12th July 2022 | 12.30pm EST | 5.30pm UKDavid S Mathai, Scott M Lee, Victoria Mora, Kelley C O'Donnell, Albert Garcia-Romeu, Eric A Storch.J Affect Disord. 2022 Sep 1;312:113-121. doi:...
30. Population pharmacokinetics and pharmacodynamics of the therapeutic and adverse effects of ketamine in patients with treatment-refractory depression
Population pharmacokinetics and pharmacodynamics of the therapeutic and adverse effects of ketamine in patients with treatment-refractory depressionTuesday, 28 June 2022 | 10:00pm (UK time)| 5:00pm (NYC time) | Wednesday, 29 June 2022, 6:30am (Adelaide, Australia –...
29. Ketamine activates adult-born immature granule neurons to rapidly alleviate depression-like behaviors in mice
Ketamine activates adult-born immature granule neurons to rapidly alleviate depression-like behaviors in miceTuesday 14th June 2022 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Radhika Rawat, Elif Tunc-Ozcan, Tammy L. McGuire, Chian-Yu Peng,...
28. Electrophysiological correlates and predictors of the antidepressant response to repeated ketamine infusions in treatment-resistant depression
Electrophysiological correlates and predictors of the antidepressant response to repeated ketamine infusions in treatment-resistant depressionTuesday 24th May 2022 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Sara de la Salle, Jennifer L...
27. Toward Synergies of Ketamine and Psychotherapy
Toward Synergies of Ketamine and PsychotherapyTuesday 10th May 2022 | 05:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)David S Mathai, Victoria Mora, Albert Garcia-Romeu.Front Psychol. 2022 Mar 25;13:868103. doi: 10.3389/fpsyg.2022.868103. PMID:...
26. Ketamine Modulates the Neural Correlates of Reward Processing in Unmedicated Patients in Remission From Depression
Ketamine Modulates the Neural Correlates of Reward Processing in Unmedicated Patients in Remission From DepressionTuesday 22nd March 2022 | 04:30 PM (UK time) | 12:30 PM (EDT NY time) | 09:30 AM (PDT LA time)Vasileia Kotoula, Argyris Stringaris, Nuria Mackes,...
25. A Cohort-Based Case Report: The Impact of Ketamine-Assisted Therapy Embedded in a Community of Practice Framework for Healthcare Providers With PTSD and Depression
A Cohort-Based Case Report: The Impact of Ketamine-Assisted Therapy Embedded in a Community of Practice Framework for Healthcare Providers With PTSD and DepressionTuesday 22nd February 2022 | 5.30 PM (UK time) | 12:30 PM (EDT NY time) | 9.30 AM (PDT LA time)Shannon...
24. A retrospective analysis of ketamine intravenous therapy for depression in real-world care settings
A retrospective analysis of ketamine intravenous therapy for depression in real-world care settingsTuesday 25th January 2022 | 5.30 PM (UK time) | 12:30 PM (EDT NY time) | 9.30 AM (PDT LA time)L. Alison McInnes, Jimmy J. Qian, Rishab S. Gargeya, Charles DeBattista,...
23. Cost-utility analysis of esketamine and electroconvulsive therapy in adults with treatment-resistant depression
Cost-utility analysis of esketamine and electroconvulsive therapy in adults with treatment-resistant depressionTuesday 11th January 2022 | 5.30 PM (UK time) | 12:30 PM (EDT NY time) | 9.30 AM (PDT LA time)Kinza Degerlund Maldi, Peter Asellus, Anna Myléus, Fredrik...
22. Ketamine induces EEG oscillations that may aid anesthetic state but not dissociation monitoring
Ketamine induces EEG oscillations that may aid anesthetic state but not dissociation monitoringTuesday 14th December 2021 | 5.30 PM (UK time) | 12:30 PM (EDT NY time) | 9.30 AM (PDT LA time)Shubham Chamadia, Jacob Gitlin, Jennifer Mekonnen, Breanna R Ethridge, Reine...
21. Antianhedonic Effect of Repeated Ketamine Infusions in Patients With Treatment Resistant Depression
Antianhedonic Effect of Repeated Ketamine Infusions in Patients With Treatment Resistant DepressionTuesday 9th November 2021 | 5.30 PM (UK time) | 12:30 PM (EDT NY time) | 9.30 AM (PDT LA time)Alina Wilkowska, Mariusz Stanisław Wiglusz, Maria Gałuszko-Wegielnik, Adam...
20. Age affects temporal response, but not durability, to serial ketamine infusions for treatment refractory depression
Age affects temporal response, but not durability, to serial ketamine infusions for treatment refractory depressionTuesday 12th October 2021 | 5.30 PM (BST UK time) | 12:30 PM (EDT NY time) | 9.30 AM (PDT LA time)Steven Pennybaker, Brian J Roach, Susanna L Fryer,...
19. Effects of Serial Ketamine Infusions on Corticolimbic Functional Connectivity in Major Depression
Effects of Serial Ketamine Infusions on Corticolimbic Functional Connectivity in Major DepressionTuesday 28th September 2021 | 12.30pm EDT NY Time | 9:30am PDT LA Time| 5.30pm BST UK TimeMegha M Vasavada, Joana Loureiro, Antoni Kubicki, Ashish Sahib, Benjamin Wade,...
18. Pilot randomized active-placebo-controlled trial of low-dose ketamine for the treatment of multiple sclerosis-related fatigue
Pilot randomized active-placebo-controlled trial of low-dose ketamine for the treatment of multiple sclerosis-related fatigueTuesday 14th September 2021 | 12.30pm EDT | 5.30pm UKKathryn C Fitzgerald, Bridget Morris, Aurash Soroosh, Alexandra Balshi, Dermot Maher, Adam...
17. Pharmacodynamic interactions between ketamine and psychiatric medications used in the treatment of depression: a systematic review
Pharmacodynamic interactions between ketamine and psychiatric medications used in the treatment of depression: a systematic reviewTuesday 27th July 2021 | 12.30pm EDT | 5.30pm UKJolien Veraart, Sanne Smith-Apeldoorn, Iris Bakker, Berber Visser, Jeanine Kamphuis,...
16. Mystical-type experiences occasioned by ketamine mediate its impact on at-risk drinking: Results from a randomized, controlled trial
Mystical-type experiences occasioned by ketamine mediate its impact on at-risk drinking: Results from a randomized, controlled trialTuesday 13th July 2021 12.30pm EST; 5.30pm UKRebecca L Rothberg, Nour Azhari, Nancy A Haug, Elias Dakwar. J Psychopharmacol. 2021...
15. A comparison of the pharmacokinetics and NMDAR antagonism-associated neurotoxicity of ketamine, (2R,6R)-hydroxynorketamine and MK-801
A comparison of the pharmacokinetics and NMDAR antagonism-associated neurotoxicity of ketamine, (2R,6R)-hydroxynorketamine and MK-801Tuesday 22nd June 2021 12.30pm EST; 5.30pm UKPatrick J Morris, Richard D Burke, Alok K Sharma, Daniel C Lynch, Leslie E Lemke-Boutcher,...
14. Translating the immediate effects of s-ketamine using hippocampal subfield analysis in healthy subjects-results of a randomized controlled trial
Translating the immediate effects of s-ketamine using hippocampal subfield analysis in healthy subjects-results of a randomized controlled trialTuesday 8th June 2021 12.30pm EST; 5.30pm UKAnna Höflich, Christoph Kraus, Ruth M Pfeiffer, Rene Seiger, Dan Rujescu, Carlos...
13. Effects of Ketamine on Rodent Fear Memory
Effects of Ketamine on Rodent Fear MemoryTuesday 25th May 2021 12.30pm EST; 5.30pm UKKwang H. Choi, Rina Y. Berman, Michael Zhang, Haley F. Spencer and Kennett D. Radford.Int J Mol Sci. 2020 Sep 28;21(19):7173. doi: 10.3390/ijms21197173. PMID: 32998470Presenter: Kwang...
12. Ketamine treatment upon memory retrieval reduces fear memory in marmoset monkeys
Ketamine treatment upon memory retrieval reduces fear memory in marmoset monkeysTuesday 11th May 2021 | 12.30pm EDT | 5.30pm UKPhilippens IHCHM, Draaisma L, Baarends G, Krugers HJ, Vermetten E. Ketamine treatment upon memory retrieval reduces fear memory in marmoset...
11. Midazolam and Ketamine Produce Distinct Neural Changes in Memory, Pain, and Fear Networks during Pain
Midazolam and Ketamine Produce Distinct Neural Changes in Memory, Pain, and Fear Networks during PainTuesday 26th April 2021 12.30pm EST; 5.30pm UKVogt KM, Ibinson JW, Smith CT, Citro AT, Norton CM, Karim HT, Popov V, Mahajan A, Aizenstein HJ, Reder LM, Fiez JA....
10. Distinct trajectories of antidepressant response to intravenous ketamine
Distinct trajectories of antidepressant response to intravenous ketamineTuesday 13th April 2021 12.30pm EST; 5.30pm UKO'Brien B, Lijffijt M, Lee J, Kim YS, Wells A, Murphy N, Ramakrishnan N, Swann AC, Mathew SJ. J Affect Disord. 2021 Mar 9;286:320-329. doi:...
9. Single, Fixed-Dose Intranasal Ketamine for Alleviation of Acute Suicidal Ideation. An Emergency Department, Trans-Diagnostic Approach: A Randomized, Double-Blind, Placebo- Controlled, Proof-of-Concept Trial
Single, Fixed-Dose Intranasal Ketamine for Alleviation of Acute Suicidal Ideation. An Emergency Department, Trans-Diagnostic Approach: A Randomized, Double-Blind, Placebo- Controlled, Proof-of-Concept TrialTuesday 23rd March 2021 12.30pm EST; 5.30pm UKDomany Y,...
8. Ketamine Alters Electrophysiological Responses to Emotional Faces in Major Depressive Disorder
Ketamine Alters Electrophysiological Responses to Emotional Faces in Major Depressive DisorderTuesday 9th March 2021 12.30pm EST; 5.30pm UKLundin NB, Sepe-Forrest L, Gilbert JR, Carver FW, Furey ML, Zarate CA Jr, Nugent AC. J Affect Disord. 2021 Jan 15;279:239-249....
7. Comparative effects of (S)-ketamine and racemic (R/S)-ketamine on psychopathology, state of consciousness and neurocognitive performance in healthy volunteers
Comparative effects of (S)-ketamine and racemic (R/S)-ketamine on psychopathology, state of consciousness and neurocognitive performance in healthy volunteersTuesday 23rd February 2021 12.30pm EST; 5.30pm UKTorsten Passie, Hans-Anton Adams, Frank Logemann, Simon D...
6. Prolonged ketamine infusion modulates limbic connectivity and induces sustained remission of treatment-resistant depression
Prolonged ketamine infusion modulates limbic connectivity and induces sustained remission of treatment-resistant depressionTuesday 9th February 2021 12.30pm EST; 5.30pm UKSiegel JS, Palanca BJA, Ances BM, Kharasch ED, Schweiger JA, Yingling MD, Snyder AZ, Nicol GE,...
5. An RCT of repeated ketamine administration for chronic post-traumatic stress disorder
An RCT of repeated ketamine administration for chronic post-traumatic stress disorderTuesday 12th January 2021 12.30pm EST; 5.30pm UKFeder A, Costi S, Rutter SB, Collins AB, Govindarajulu U, Jha MK, Horn SR, Kautz M, Corniquel M, Collins KA, Bevilacqua L, Glasgow AM,...
4. Sex-specific neurobiological actions of prophylactic (R,S)-ketamine, (2R,6R)-hydroxynorketamine, and (2S,6S)-hydroxynorketamine.
Sex-specific neurobiological actions of prophylactic (R,S)-ketamine, (2R,6R)-hydroxynorketamine, and (2S,6S)-hydroxynorketamine. Tuesday 22nd December 2020 12.30pm EST; 5.30pm UKChen BK, Luna VM, LaGamma CT, Xu X, Deng SX, Suckow RF, Cooper TB, Shah A, Brachman RA,...
3. The effectiveness of intravenous ketamine in adults with treatment-resistant major depressive disorder and bipolar disorder presenting with prominent anxiety: Results from the Canadian Rapid Treatment Center of Excellence
The effectiveness of intravenous ketamine in adults with treatment-resistant major depressive disorder and bipolar disorder presenting with prominent anxiety: Results from the Canadian Rapid Treatment Center of ExcellenceTuesday 8th December 2020 12.30pm EST; 5.30pm...
2. Long-term outcome in outpatients with depression treated with acute and maintenance intravenous ketamine: A retrospective chart review
Long-term outcome in outpatients with depression treated with acute and maintenance intravenous ketamine: A retrospective chart reviewTuesday 24th November 2020 12.30pm EST; 5.30pm UKSakurai H, Jain F, Foster S, Pedrelli P, Mischoulon D, Fava M, Cusin C. J Affect...
1. Ketamine normalizes subgenual cingulate cortex hyper-activity in depression
Ketamine normalizes subgenual cingulate cortex hyper-activity in depressionTuesday 10th November 2020 12.30pm EST; 5.30pm UKMorris LS, Costi S, Tan A, Stern ER, Charney DS, Murrough JW. Neuropsychopharmacology (2020), 45(6):975-981.PMID: 31896116Presenter: Laurel S....